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KMID : 1134819990280010233
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Journal of the Korean Society of Food Science and Nutrition
1999 Volume.28 No. 1 p.233 ~ p.239
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Effects of Fermented Milk Feeding on Function and Suppression of Aluminum Accumulation in Kidney of Rat
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Kim Joong-Man
Park Seong-Soo
Baek Seung-Hwa
Chung Dong-Hyun
Choi Yong-Bae
Shin Yong-Seo
Han Seong-Hee
Hong Ga-Hyung
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Abstract
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This study was performed to evaluate the effects of the supplementation of lactic acid bacterias (LAB; S. thermophilus, L. acidophilus) aluminum accumulation and function kidney in rats treated with 250㎍/g aluminum sulfate for 4 weeks. Fifty male Sprague-Dawley strains were divided into five groups according to the types of supplement. the control, S. thermophilus culture group(A), autoclaved S. thermophilus culture(B), L. acidophilus culture group(C) and autoclaved L. acidophilus(D). The weight gain was increased by supplementation of S. thermophilus culture(A), autoclaved S. thermophilus culture(B), L. acidophilus culture(C), autoclaved L. acidophilus culture(D), especially by supplementation of S. thermophilus cultured(A) as compared to control group. The amount of water intake was increased in control group as compared to the LAB supplemented group. The content of aluminum were decreased 19.57%, 31.25%, 37.10%, and 32.40% in kidney after supplementation of non-autoclaved culture group (A,C), and autoclaved group(B,D) respectively, as compared to control group. Water balance, urine volume, and excretion of sodium and potassium decreased in LAB supplemented group and control group. Excretion of creatinine increased in control group and tendency to increased in LAB supplemented group. In conclusion, the effect of suppression of aluminum accumulation was more effective in supplementation of S. thermophilus culture(A), and L. acidophilus culture(C) than autoclaved S. thermophilus culture(B), and L. acidophilus culture(D).
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KEYWORD
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aluminum sulfate, kidney functions, suppression of aluminum accumulation, lactic acid bacteria
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